Grey Matter Volume and Fractional Anisotropy as Correlates of Cognitive Improvement in Traumatic Brain Injury over a 6-month Period 1058

Thursday, October 30, 2025

11:15 AM - 11:30 AM

Location: ROOM: Conference Room 4C >>> DIRECTIONS Fourth Floor >>> From the Main Elevator Bank, proceed left. Room 4C is at the end of the corridor, just beyond 4D

Presenting Author(s)

Emily R. Rosario, n/a

Director of Research
Casa Colina Hospital and Centers for Healthcare
Pomona, California, United States

Slides Slides

Non-presenting Author(s)

BZ

Benjamin Zhang

RA
Casa Colina Hospital and Centers for Healthcare
Pomona, California, United States
Niko Fullmer, BS

Research Project Supervisor
Casa Colina Hospital and Centers for Healthcare
Pomona, California, United States
SD

Sarah Dunn

Professor
CSLASB
Pomona, California, United States
ZZ

Zhong Sheng R. Zheng

Research Scientist
Casa Colina Hospital and Centers for Healthcare
Pomona, California, United States
Caroline R. Schnakers, PhD

Associate Director of Research
Casa Colina Hospital and Centers for Healthcare
Pomona, CA, United States

This study investigates the relationship between structural brain changes and cognitive recovery in individuals with traumatic brain injury (TBI) over a six-month period. Specifically, it explores how variations in grey matter volume (GMV) and fractional anisotropy (FA)—a measure of white matter integrity—correlate with improvements in cognitive function.

Learning Objectives:

Discuss how changes in grey matter volume and fractional anisotropy, as assessed by MRI and diffusion tensor imaging (DTI), correlate with cognitive recovery over a six-month period.
discuss insights into the use of the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), Disability Rating Scale, and Montreal Cognitive Assessment (MoCA) in measuring neuropsychological and functional recovery in TBI patients.
Explore the role of blood biomarkers in the study and understand why they did not show significant correlation with cognitive recovery, compared to neuroimaging markers.