Assistant Professor
Wayne State University, Department of Veteran Affairs
Dr. Panza’s lab is currently investigating the autonomic control of blood pressure in individuals living with spinal cord injuries (SCI). His lab also investigates the impact of sleep disruption on rehabilitation efforts. Individuals with SCI have two distinct cardiovascular responses called orthostatic hypotension (drops in blood pressure) and autonomic dysreflexia (spikes in blood pressure). Both of these blood pressure responses significantly impact physical function, activities, and restrict participation in society. Currently, the lab is investigating 8 days of mild intermittent hypoxia can improve blood pressure control in individuals with SCI. Additionally, the lab is investigating if the neuroplastic changes in the control of breathing change over time, and if they improve during sleep. Finally, the lab is exploring mitochondrial adaptations following mild intermittent hypoxia, and if it contributes to autonomic dysfunction in this group. Primary measures obtained during our studies include, but are not limited to; heart rate and blood pressure variability, pulmonary function, electrocardiograms, muscle oxygenation, and motor limb function (hand and leg).
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