Post-traumatic Confusional State: Pathophysiology and Biomarkers Related to Diagnosis and Prognosis - A Scoping Review

Thursday, October 30, 2025

11:15 AM - 11:30 AM

Location: ROOM: Conference Room 4G >>> DIRECTIONS Fourth Floor >>> From the Main Elevator Bank, proceed left. Turn left at the Pullman Boardroom. Room 4G is at the end of the corridor.

Presenting Author(s)

Douglas I. Katz, MD (he/him/his)

Professor / Medical Director
Boston University / Encompass Health Braintree Rehab
Newton Center, MA, United States

Slides Slides
Yelena Bodien

Assistant Professor
Vanderbilt University Medical Center
Nashville, Tennessee, United States

Non-presenting Author(s)

AF

Afik Faerman

Neuropsychologist
Boulder Neuropsychological Services
Littleton, Colorado, United States
Bei Zhang, MD, MSc

Associate Professor
Texas Tech University Health Sciences Center
Lubbock, Texas, United States
EM

Emma-Jane Mallas

Postdoctoral Research Associate
Imperial College London
London, England, United Kingdom
Natalie M. Gilmore, PhD, CCC-SLP (she/her/hers)

Early Career Investigator
James A. Haley Veterans' Hospital
Tampa, Florida, United States
SB

Sonja Blum, MD, PhD

Assoc Professor
Weill Cornell Medicine
New York, New York, United States
Yelena Bogdanova, PhD, PhD

Assistant Professor
Boston University
Newton, Massachusetts, United States
Jessica V G Correa, PT, MSc

Lecturer
Universidade Federal do Espirito Santo
Cariacica, Espirito Santo, Brazil
BD

Brigid Dwyer, MD

Assistant Professor
Boston University, Dept of Neurology
Braintree, Massachusetts, United States
Min Jeong P. Graf, MD

Chair, Dept of PM&R, Medical Director, Outpatient TBI program, Assistant Professor
Hennepin Healthcare, Dept of PM&R, Unniversity of Minnesota, Dept of Rehab Medicine
Minneapolis, Minnesota, United States
KH

Keira Hays, PhD, ABPP-CN

Neuropsychologist
Craig Hospital
Littleton, Colorado, United States
Michael H. Marino, MD

Attending Physician
Moss Rehab- Jefferson Health
Elkins Park, Pennsylvania, United States
Amy M. Shapiro-Rosenbaum, PhD (she/her/hers)

Director of Neuropsychological Rehabilitation and Director of Research
Park Terrace Care Center
Flushing, New York, United States
Julie Schwertfeger, PhD, DPT, MBA

Assistant Professor
Louisiana State University Health Shreveport
Shreveport, Louisiana, United States
MS

Mark Sherer, Ph.D., ABPP, FACRM

Consultant
Model Systems Knowledge Translation Center
Temecula, California, United States
Michael W. Williams, Ph.D.

Assistant Professor
University of Houston
Houston, Texas, United States

Learning Objectives:

understand the range of available research on imaging, electrophysiologic, protein genetic and other biomarkers that inform understanding of the pathophysiology of the post-traumatic confusional state (PTCS).
describe key research findings on biomarkers that may help inform diagnosis and prognosis with respect to PTCS in patients with TBI.
discuss whether biomarkers have the potential to improve the diagnostic criteria for PTCS.